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Research

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> "De novo genic mutations among a Chinese autism spectrum disorder cohort." was online published in Nature Communications.

November 8, 2016

> "Altered Expression of EPO Might Underlie Hepatic Hemangiomas in LRRK2 Knockout Mice." was online published in BioMed Research International.

October 31, 2016

> "WDR73 missense mutation causes infantile onset intellectual disability and cerebellar hypoplasia in a consanguineous family." was online published in ScienceDirect.

October 28, 2016

> "Risperidone-induced topological alterations of anatomical brain network in first-episode drug-naive schizophrenia patients: a longitudinal diffusion tensor imaging study." was online published in Psychological Medicine.

June 24, 2016

> "mtDNA Heteroplasmy in Monozygotic Twins Discordant for Schizophrenia." was online published in Mol Neurobiol.

June 24, 2016

> "Analyses MAPT, GRN, and C9orf72 mutations in Chinese patients with frontotemporal dementia." was online published in Neurobiology Of Aging.

May 20, 2016

> "AKAP2 identified as a novel gene mutated in a Chinese family with adolescent idiopathic scoliosis." was online published in Journal of Medical Genetics.

March 17, 2016

> "Identification of RELN variation p.Thr3192Ser in a Chinese family with schizophrenia." was online published in Scientific Reports.

April 13, 2016


> "High prevalence of CHCHD10 mutation in patients with frontotemporal dementia from China." was online published in Brain A Journal of Neurology.

December 30, 2015


> "Protein 4.1N acts as a potential tumor suppressor linking PP1 to JNK-c-Jun pathway regulation in NSCLC." was online published in Oncotarget.

November 13, 2015


> "miR-150 inhibits terminal erythroid proliferation and differentiation." was online published in Oncotarget.

November 3, 2015


> "Psychiatric genetics in China: achievements and challenges." was online published in Mol Psychiatry.

October 20, 2015


> "Pathogenic Cx31 is un/misfolded to cause skin abnormality via a Fos/JunB-mediated mechanism." was online published in Hum Mol Genet.

August 6, 2015


> "Genes with de novo mutations are shared by four neuropsychiatric disorders discovered from NPdenovo database." was online published in Molecular Psychiatry.

Apr 7, 2015


> "Novel Mutations of Low-Density Lipoprotein Receptor Gene in China Patients with Familial Hypercholesterolemia." was online published in Applied Biochemistry and Biotechnology.

Apr 7, 2015


> "mirTrios: an integrated pipeline for detection of de novo and rare inherited mutations from trios-based next-generation" was online published in Journal of Medical Genetics.

Apr 1, 2015


> "Neuropeptide Receptors NPR-1 and NPR-2 Regulate Caenorhabditis elegans Avoidance Response to the Plant Stress Hormone Methyl Salicylate." was online published in Genetics.

Feb 5, 2015


> "Methylation profiling of 48 candidate genes in tumor and matched normal tissues from breast cancer patients." was online published in Breast Cancer Research and Treatment.

Feb 1, 2015


> "Mutations of P4HA2 encoding prolyl 4-hydroxylase 2 are associated with nonsyndromic high myopia" was online published in Clinical Chemistry.

Mar 5, 2015



> "Association of genetic variants of GRIN2B with autism" was online published in Clinical Chemistry.

Feb 6, 2015


> "Non-invasive Prenatal Testing for Wilson Disease by Use of Circulating Single-Molecule Amplification and Resequencing Technology (cSMART)" was online published in Clinical Chemistry.

Nov 6, 2014


> "Correlation between DNA methylation and gene expression in the brains of patients with bipolar disorder and schizophrenia" was online published in Bipolar Disorders.

Sep 22, 2014


> "SLC39A5 mutations interfering with the BMP/TGF-β pathway in non-syndromic high myopia" was online published in Journal of Medical Genetics.

Jun 2, 2014


> "Molecular network analysis enhances understanding of the biology of mental disorders" was published in BioEssays.

Jun, 2014


> "Functional Rescue of Kallmann Syndrome-associated PKR2 Receptor Mutants Deficient in Trafficking" was online published in The Journal of Biological Chemistry.

Apr 21, 2014


> "Mechanisms that underlie the internalization and extracellular signal regulated kinase 1/2 activation by PKR2 receptor" was online published in Cellular Signalling.

Feb 11, 2014


> "Common genetic variants on 1p13.2 associate with risk of autism" was online published in Molecular Psychiatry.

Nov 5, 2013


> "Homozygous loss-of-function mutation of the LEPREL1 gene causes severe non-syndromic high myopia with early-onset cataract" was online published in Clinical Genetics.

Oct 30, 2013


> "MicroRNA/mRNA profiling and regulatory network of intracranial aneurysm" was online published in BMC Medical Genomics.

Sep 30, 2013


> "A novel deletion to normal size in the sperm of a fragile X full mutation male" was online published in Clinical Genetics.

Sep 23, 2013


> "Functional analysis of the distal region of the third intracellular loop of PROKR2" was published in Biochemical and biophysical research communications.

Sep 13, 2013


> "Phenotypic expansion of the interstitial 16p13.3 duplication: A case report and review of the literature" was online published in Gene.

Sep 12, 2013

> "Increased expression of reticulon 3 in neurons leads to reduced axonal transport of β-site amyloid precursor protein cleaving enzyme " was online published in The Journal of Biological Chemistry.

Sep 4, 2013

> "Using next-generation sequencing as a genetic diagnostic tool in rare autosomal recessive neurologic Mendelian disorders" was online published in Neurobiology of Aging.

May 30, 2013

> "Nonviral Gene Targeting at rDNA Locus of Human Mesenchymal Stem Cells" was online published in Biomed Research International.

May 15, 2013

> "SUMO-1 modification on K166 of polyQ-expanded ataxin-3 strengthens its stability and increases its cytotoxicity" was online published in PloS one.

Janurary 31, 2013

> "Sodium valproate alleviates neurodegeneration in SCA3/MJD via suppressing apoptosis and rescuing the hypoacetylation levels of histone H3 and H4" was online published in PloS one.

Janurary 28, 2013

> "hF-measure: A new measurement for evaluating clusters in protein-protein interaction networks" was online published in Human Molecular Genetics.

November 30, 2012

> "Exome sequencing identifies MVK mutations in disseminated superficial actinic porokeratosis" was online published in Nature Genetics.

September 16, 2012

> "Clinical Reasoning: A young man with reversible paralysis, cerebral white matter lesions, and peripheral neuropathy" was published in Neurology.

August 21, 2012


> "The Caenorhabditis elegans Gene mfap-1 Encodes a Nuclear Protein That Affects Alternative Splicing" was published in PLoS Genetics.

July 19, 2012


> "Three patients with Wolf-Hirschhorn syndrome carrying a satellited chromosome 4p" was published in Birth Defects Res A Clin Mol Teratol.

May 29, 2012


> “Targeting of the Human Coagulation Factor IX Gene at rDNA Locus of Human Embryonic Stem Cells” was published in PLoS One.

May 16, 2012


> “A novel splicing mutation in COL1A1 gene caused type I osteogenesis imperfecta in a Chinese family” was published in Gene.

Apr 29, 2012


> “Loss-of-function mutations in filaggrin gene associate with psoriasis vulgaris in Chinese population” was published in Human Genetics.

March 11, 2012


> “Mutation analysis of the NRXN1 gene in a Chinese autism cohort” was published in Journal of Psychiatric Research.

March 9, 2012


> “ Pathogenic connexin-31 forms constitutively active hemichannels to promote necrotic cell death” was published in PLoS One.

Feburary 29, 2012


   

Science News

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> Pilot Analysis from GTEx Project Illuminates Gene Expression Variation in Different Tissues

> Mechanism outlined by which inadequate vitamin E can cause brain damage

> Gene-hunt gain for mental health

> One injection stops diabetes in its tracks: Treatment reverses symptoms of type 2 diabetes in mice without side effects

> Functioning of aged brains and muscles in mice made younger

> Free online software helps speed up genetic discoveries

> Scientists identify the switch that says it's time to sleep

> Whole genome analysis, stat

> Zebrafish neurons may lead to understanding of birth defects like spina bifida

> Brain aging is conclusively linked to genes

> Effects of chronic stress can be traced to your genes

> A New Wrinkle in Parkinson’s Disease Research

> Rules governing expression of developmental genes in mouse embryonic stem cells are more nuanced than anticipated

> Genetic mutations linked to Parkinson's disease

> Neuroscientists identify protein linked to Alzheimer's-like afflictions

> Jammed molecular motors may play a role in the development of ALS

> Context Crucial When It Comes to Mutations in Genetic Evolution

> Study finds brain system for emotional self-control

> A cautionary tale on genome-sequencing diagnostics for rare diseases

> Divide and define: Clues to understanding how stem cells produce different kinds of cells

> Genome sequencing provides unprecedented insight into causes of pneumococcal disease

> Epilepsy cured in mice using brain cells

> New Cost-Effective Genome Assembly Process

> Scientists create novel approach to find RNAs involved in long-term memory storage

> New research findings on the brain's guardian cells

> Epigenetic changes shed light on biological mechanism of autism

> New technique helps understanding the connectivity of neural circuits in the brain

> President Barack Obama will spend $100 million to study brain disorders

> Brain Project Draws Presidential Interest

> Obama Seeking to Boost Study of Human Brain

> One gene, many mutations

> International consortium builds 'Google Map' of human metabolism

> International consortium discovers seven new genomic regions associated with AMD

> Taking the Gamble out of DNA Sequencing: How Much Can Be Learned in a Large-Scale Experiment

> Scientists Find Genes Linked to Human Neurological Disorders in Sea Lamprey Genome

> Researchers show how cells' DNA repair machinery can destroy viruses

> Novel gene-searching software improves accuracy in disease studies

> Parkinson's treatment can trigger creativity

> Rare form of active 'jumping genes' found in mammals

> Cheap and Easy Technique to Snip DNA Could Revolutionize Gene Therapy

> Tracking the Origins of HIV

> Key Gene for Brain Development

> Team Solves Mystery Associated With DNA Repair

> Learning to Control Brain Activity Improves Visual Sensitivity

> Telomere length linked to risk of dying Large study examines association

> Flu During Pregnancy May Be Linked to Autism Risk

> Telomere length linked to risk of dying Large study examines association

> Your brain on speed dating

> Multiple Similarities Discovered Between Cancer Cells and Induced Pluripotent Stem Cells

> Alzheimer's 'early signs timeline developed'

> Gene Mutation May Lead to Cognitive Symptoms in Parkinson’s

> Brain scans detect early signs of autism

> Genetic discovery will help fight diarrhoea outbreaks

> Deviation of innate circadian period from 24 hours reduces longevity in mice

> Loneliness Linked to Death, Disability

> Patients' Skin Cells Turned Into Heart Muscle Cells to Repair Their Damaged Heart

> Rapid DNA Sequencing May Soon Be Routine Part of Each Patient's Medical Record

> Neurodegeneration 'Switched Off' in Mice

> Robot reveals the inner workings of brain cells

> Orangutans Host Ancient Jumping Genes

> Sunscreen Ingredient May Increase Skin Cancer Risk

> A new Direction? Fat Future: 42% of Americans May Be Obese by 2030

> Evolution seen in 'synthetic DNA'




   

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